STAT1 rs11889341: what the research says
A driver SNP associated with Primary Antiphospholipid Syndrome (PAPS) that influences disease susceptibility.
What each genotype means
Baseline risk profile
This genotype is not associated with the increased risk for Primary Antiphospholipid Syndrome (PAPS) identified in studies of this variant. Your genetic profile at this position is consistent with the lower-risk baseline. Always consult with a healthcare provider regarding any symptoms or concerns about autoimmune health.
This genotype is common in many populations.
Intermediate risk profile
Carrying one copy of this variant may be associated with a different level of susceptibility to Primary Antiphospholipid Syndrome (PAPS) compared to the baseline. Genetic associations are complex and influenced by many factors. Please discuss your overall health and any relevant family history with your doctor.
This genotype is found at variable frequencies across different ancestral groups.
Increased risk profile
This genotype has been identified in research as a driver variant associated with susceptibility to Primary Antiphospholipid Syndrome (PAPS). While this is a statistical association, it does not guarantee the development of the condition. You should discuss this finding with a clinician to determine if any monitoring is appropriate for your health.
This genotype is found at variable frequencies across different ancestral groups.
Variable
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