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ZMAT4 rs16890057: what the research says

rs16890057
Vision
Limited evidenceGene: ZMAT4

This SNP is linked to variations in spherical equivalent refraction and spherical power, contributing to refractive error phenotypes in pediatric cohorts.

What each genotype means

A/ALower attention

Typical refractive development

This genotype is associated with standard ocular growth patterns in pediatric cohorts. Research suggests it may influence spherical equivalent refraction, though the effect size is modest.

This genotype is common in East Asian populations.

A/GLower attention

Varied refractive development

Carriers of this genotype may show slight variations in spherical power and axial length during childhood. Evidence for this association is limited and primarily observed in East Asian pediatric studies.

This genotype is frequently observed in East Asian populations.

G/GModerate attention

Associated with refractive variation

This genotype has been associated with changes in spherical equivalent refraction and axial length in children. These findings are based on statistical associations in East Asian cohorts and should not be used for clinical diagnosis.

This genotype is common in East Asian populations.

Common in East Asian populations

Our full long-form research profile for rs16890057 — genotype interpretations, evidence review, and FAQ — is being written and will appear on this page soon.

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Related variants in ZMAT4