PER3 rs17031614: what the research says
This variant in the PER3 gene is associated with altered chronotype and increased risk of mood and sleep disorders in young adults.
A-allele frequency approximately 0.04
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A missense variant (p.Pro415Ala) in PER3 associated with morning-evening preference, extreme diurnal preference, and delayed sleep phase syndrome.
Associated with individual variability in circadian phase and diurnal preference (extreme morningness vs eveningness chronotypes).
This missense variant (p.His417Arg) in the PER3 gene is associated with Familial Advanced Sleep Phase Syndrome (FASP) and extreme morning chronotype.
This variant in the PER3 circadian clock gene is associated with chronotype, sleep homeostasis, delayed sleep phase syndrome, and metabolic health markers including type 2 diabetes risk.
This missense variant (Pro415Ala) in the PER3 gene is associated with familial advanced sleep phase syndrome and extreme morning chronotype.
This missense variant (M1037T) in the PER3 circadian clock gene is associated with variations in sleep timing and phase.