MSH2 rs267607691: what the research says
This variant is a pathogenic mutation associated with Lynch syndrome, which can impact reproductive health and cancer risk management.
What each genotype means
Lynch syndrome risk
This genotype indicates the presence of a pathogenic mutation in the MSH2 gene, which is associated with an increased risk of developing Lynch syndrome. Individuals with this finding should consult with a genetic counselor or physician to discuss appropriate cancer screening and risk management strategies.
This is a rare genotype found in individuals with a clinical or familial history of Lynch syndrome.
Rare
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Pathogenic DNA mismatch repair variant predisposing to Lynch syndrome and high risks of colorectal and endometrial adenocarcinomas.
This SNP is investigated for its role in DNA repair pathways and potential association with Lynch syndrome and gallbladder cancer predisposition.