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IL18 rs5744292: what the research says

rs5744292
Nutrigenomics
Limited evidenceGene: IL18

This variant interacts with sodium intake to influence blood pressure outcomes.

What each genotype means

A/ALower attention

Typical IL18 expression profile

This genotype is associated with standard IL-18 expression levels in many populations. Research suggests this variant may interact with dietary sodium intake to influence blood pressure, though the evidence for this specific effect remains limited and requires further study.

This is a common genotype found across many global populations, though exact frequencies vary significantly by ancestry.

A/GLower attention

Typical IL18 expression profile

Carriers of this genotype possess one copy of each allele. Studies indicate that this variant may play a role in how your body responds to dietary sodium regarding blood pressure regulation, but current scientific evidence is limited and not definitive.

This heterozygous genotype is frequently observed in diverse populations worldwide.

G/GModerate attention

Potential altered expression profile

This genotype has been studied in the context of IL-18 gene expression and its potential interaction with dietary sodium and blood pressure outcomes. Because the evidence linking this variant to health outcomes is limited, it is not a diagnostic marker; please discuss any concerns about blood pressure or diet with your healthcare provider.

This genotype is present in many populations, with frequency distributions that differ based on ancestral background.

Varies by ancestry

Our full long-form research profile for rs5744292 — genotype interpretations, evidence review, and FAQ — is being written and will appear on this page soon.

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Related variants in IL18