DOCK7 rs636523: what the research says
This variant is associated with triglyceride levels and shows consistent effects across diverse ancestral groups, including African Americans.
What each genotype means
Baseline triglyceride association
This genotype represents the common form of the DOCK7 variant. Research indicates this variant is associated with triglyceride levels, though the effect size is generally small and the clinical significance remains limited.
This is the most common genotype in many populations, though exact frequencies vary significantly by ancestral background.
Variable triglyceride association
Carriers of this genotype possess one copy of the variant associated with triglyceride levels. Studies suggest this variant shows consistent effects across diverse ancestral groups, including African Americans, but it should not be used to predict individual health outcomes.
This heterozygous genotype is found at varying frequencies across global populations.
Alternative triglyceride association
This genotype represents the less common form of the variant. While associated with triglyceride levels in genome-wide association studies, the evidence is limited and does not constitute a diagnostic indicator for lipid-related health conditions.
This genotype is the least common of the three and its prevalence is highly dependent on ancestral origin.
Variable across ancestral groups
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