LOC130067884 rs6010014: Understanding This Genetic Variant
The genetic variant rs6010014 is a single nucleotide polymorphism located within the LOC130067884 gene region. It is currently annotated as a benign, non-coding variant in clinical databases, meaning it is not known to cause disease.
What each genotype means
Common genetic variant
This genotype represents the homozygous state for this non-coding variant. Current clinical databases classify this variant as benign, meaning it is not associated with known disease conditions.
Specific population frequency data for this genotype is not currently available in public clinical databases.
Common genetic variant
This genotype represents the heterozygous state for this non-coding variant. Current clinical databases classify this variant as benign, meaning it is not associated with known disease conditions.
Specific population frequency data for this genotype is not currently available in public clinical databases.
Common genetic variant
This genotype represents the homozygous state for this non-coding variant. Current clinical databases classify this variant as benign, meaning it is not associated with known disease conditions.
Specific population frequency data for this genotype is not currently available in public clinical databases.
What is rs6010014?
The identifier rs6010014 refers to a specific single nucleotide polymorphism (SNP) in the human genome. In genetics, a SNP represents a variation at a single position in a DNA sequence among individuals. This particular variant is located within the genomic region associated with the gene LOC130067884. Because it is classified as a non-coding variant, it does not reside within the protein-coding sequence of a gene, which is where instructions for building proteins are typically found. Instead, it sits in the surrounding DNA, which can sometimes play a role in regulating how genes are turned on or off. In the context of clinical databases like ClinVar, rs6010014 is currently labeled as benign. This classification indicates that, based on the evidence available to researchers and clinicians, this specific change in the DNA sequence is considered a normal variation rather than a cause of a medical condition or health disorder.
Understanding the LOC130067884 Gene
The gene LOC130067884 is identified in genomic databases as a functional element. Research into this specific region has utilized techniques such as ATAC-STARR-Seq, which is a method used to identify regulatory elements in the genome that can influence gene expression. Specifically, this region has been studied in lymphoblastoid cell lines, which are white blood cells that have been immortalized for research purposes. While the gene is categorized as a functional element, it is not a traditional protein-coding gene that produces a well-characterized protein product. Instead, it is often studied for its potential role in the complex regulatory landscape of the human genome. Genomic research continues to map these functional elements to better understand how non-coding regions contribute to cellular processes and how variations in these areas might influence biological traits, even if they do not directly result in a disease-causing mutation.
Research and Evidence Strength
The evidence supporting the clinical significance of rs6010014 is currently limited. In the scientific community, variants are often evaluated based on their association with specific traits or diseases through Genome-Wide Association Studies (GWAS). While the GWAS Catalog serves as a comprehensive resource for these associations, rs6010014 does not currently have strong, established links to specific clinical phenotypes or health outcomes in the published literature. The classification of 'benign' in ClinVar reflects the current consensus that this variant is a common, harmless piece of genetic diversity. It is important to note that genetic research is an evolving field; as more data is collected and more individuals are sequenced, our understanding of such variants may be refined. However, at this time, there is no evidence to suggest that this variant requires clinical attention or that it serves as a marker for any specific medical condition.
What You Can Do With This Information
If you have encountered rs6010014 in a personal genetic report, it is helpful to understand that this variant is considered a normal part of human genetic variation. Because it is classified as benign and is not associated with any known disease, it generally does not provide actionable health information. You do not need to take any medical action or change your lifestyle based on this specific result. Genetic reports can sometimes be complex, and it is common to see many variants listed that have no impact on your health. If you have concerns about your genetic data or your family health history, the best course of action is to consult with a qualified healthcare provider or a genetic counselor. They can help you interpret your results in the context of your overall health and provide guidance that is tailored to your specific needs, rather than focusing on individual, non-pathogenic variants.
How common is this variant?
The variant rs6010014 is a common genetic polymorphism, though specific frequency data across diverse global populations is not explicitly detailed in current public catalog summaries.
Frequently asked questions
Is rs6010014 associated with any diseases?
No, rs6010014 is currently classified as a benign variant in clinical databases. There is no evidence linking it to any specific disease or health condition.
Should I be worried if I have this variant?
There is no reason to be concerned. This variant is considered a normal part of human genetic diversity and is not known to have any negative impact on your health.
What does 'benign' mean in a genetic report?
In genetics, 'benign' means that the variant is not expected to cause a disease or health problem. It is essentially a harmless difference in your DNA sequence.
Do I need to see a doctor about this result?
Generally, no. Since this variant is benign and common, it does not require medical follow-up. However, you should always speak with a healthcare provider if you have general concerns about your genetic health.
Sources & further reading
Educational information only, last refreshed 9/15/2026. Not medical advice — these associations describe population statistics, not individual predictions.
Curious what your genotype is for rs6010014?
Upload a raw DNA file from 23andMe, AncestryDNA, MyHeritage, or FamilyTreeDNA and see this variant — plus thousands more — interpreted in your full report.
Get my report — $29